Family runs deep in the NFL, and two San Francisco 49ers captains showed that their support extends beyond team colors.

The 49ers A.P.E.X. Employee Resource Group came together to create an apparel line that pays homage to the roots of AAPI ...

John Lynch detailed why rookie guard Dominick Puni's 2024 NFL season success could serve as San Francisco's blueprint for ...

The San Francisco 49ers fired defensive coordinator Nick Sorensen after just one disappointing season, a person familiar with ...

Kyler Murray, who throws 4 TD passes in a Cardinals victory that leaves SF with a disappointing 6-11 season finish.

The Detroit Lions and San Francisco 49ers play Monday, Dec. 30, at the 49ers' Levi's Stadium in a game on the NFL Week 17 schedule. Which team will win the Monday Night Football game? Check out ...

The Detroit Lions meet the San Francisco 49ers on Monday Night Football at Levi's Stadium in Santa Clara, California to finish Week 17 of the 2024 NFL season. The Lions (13-2) will be playing ...

He sat out the 49ers' Week 16 loss at Miami due to the health concerns, and Saturday's practice report may provide a sense of his odds to return to action Monday against the Lions. If he's cleared ...

George Kittle didn't have a catch. All three players, though, made big plays in the second half as the San Francisco 49ers rallied from 17 points down to beat the Detroit Lions and advance to the ...

And yet you guys managed to bring thoughtfulness — and even some mirth — to this week’s San Francisco 49ers holiday mailbag. Well done! I hope your stockings were full of frankincense and myrrh.