Recent studies show that hyperactivation of mTOR (mammalian target of rapamycin) signaling plays a causal role in the development of thoracic aortic aneurysm and dissection ... mitigate AA progression ...

Background: Loeys–Dietz syndrome (LDS) is a clinically and genetically heterogeneous, autosomal dominant aortic aneurysm syndrome with widespread systemic involvement. We present the case of a ...

In discussion, the terms “thoracic aortic dissection” and “abdominal aortic aneurysm” (AAA ... One-fourth of patients with Marfan syndrome will develop dissection. The Stanford and ...